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2013年9月26日星期四

New canine cancer research from North Carolina State (USA)

NC State Researchers Find Soy May Aid in Treating Canine Cancers



Researchers at North Carolina State University are looking to soy as a way to make traditional canine cancer therapy more effective, less stressful for the dog and less costly for the owners.


Dr. Steven Suter, assistant professor of oncology, and NC State colleagues studied genistein – a molecule found in soy that has been shown to be toxic to a wide variety of cancer cells in humans – to determine whether it would also inhibit the growth of canine lymphoma cells.


The researchers found that a commercially available form of genistein called GCP was effective in killing canine lymphoid cells in a laboratory setting, and that GCP is “bioavailable” in canines – meaning it is absorbed into the bloodstream where it can affect cancer cells in the body. The researchers hope that their findings will lead to the use of GCP for their canine patients in conjunction with traditional cancer treatments like chemotherapy.


The researchers’ findings were published in Clinical Cancer Research.


“Humans have been using soy in conjunction with traditional chemotherapy for some time as a chemo potentiator,” Suter says. “This means that the GCP makes the chemotherapy work more efficiently and faster, which translates to less stress on the patient and less money spent on chemotherapy.”


Since dogs absorb GCP in much the same way that humans do, Suter hopes that veterinarians will be able to offer this therapy to canine patients in the near future.


“Since GCP is a dietary supplement, it is harmless to patients,” he adds. “Plus it’s inexpensive and easy to administer in a pill form. There’s really no downside here.”



Source: http://v3.news.ncsu.edu/releases/nc-state-researchers-find-soy-may-aid-in-treating-canine-cancers/


2013年9月22日星期日

May 6, 2010 - Angel"s Leukopheresis Procedure at NC State!


Hi everyone, 


Dr. Suter called last night to let us know that Angel is still 100% cancer free! They moved forward and performed the Leukopheresis Procedure today. This is procedure will harvest Angel’s stem cells for implantation tomorrow; it’s sort of like dialysis. Angel was placed under light sedation; Dr. Suter had to speak quietly so he didn’t wake her.




The procedure is painless in humans, but they often complain of being cold. They assume that it’s the same for dogs, so they put a blanket over them to keep them warm.



These pictures were received a few hours ago while Angel was receiving the Leukopheresis Procedure at NC State!



The machine was running for 4-5 hours and then Dr. Suter called with wonderful news! Angel produced 1.7 million more cells than needed for the transplant! 


Humans sometimes save these cells, but Dr. Suter gives them all back to the dogs :)  



The more cells there are to pump in, the higher Angel’s odds are of living cancer free for the rest of her long and happy life!





Tomorrow morning at 7am EST Angel will be prepped for full body irradiation. She will receive 2 doses of radiation in 1 hour intervals and Angel will be heavily sedated for the duration of the procedures.




They will take a 3 hour break between each hour on. After the radiation is complete Angel will receive her life-saving Canine Bone Marrow Transplant! This procedure has “taken” every time and they expect Angel to sail through with ease :)  



The irradiation will wipe out Angel’s immune system, so a clean environment is critical to her recovery. She will wake up in ICU in a completely sterile room, safe from any outside germs or bacteria.


Thank you for following Angel’s progress!  I’ll keep you all updated as information comes in.  


Please visit our website for more information, http://www.save-an-angel.org/events.html and to donate to Angel’s life-saving treatment!  Please help us spread the word :)  
     

Most Sincerely,

Kristie Sullens — Angel’s Mama
xoxoxoxoxoxoxox